Tag Archives: COVID-19

World Oil: ExxonMobil joins COVID-19 fight, helping develop multi-use PPE for clinical settings

IRVING, TEXAS – ExxonMobil and the Global Center for Medical Innovation (GCMI) have initiated multi-sector and joint development projects to rapidly redesign and manufacture reusable personal protection equipment for health care workers, such as face shields and masks, which are in short supply as a result of the COVID-19 pandemic.

In response to the unprecedented challenges from the COVID-19 pandemic, ExxonMobil is applying its deep knowledge and experience with polymer-based technologies in combination with GCMI to facilitate development and expedite third-party production of innovative safety equipment that can be sterilized and worn multiple times.

A new industrial-style mask is being fast-tracked for production. The design improves coverage of a health care worker’s nose and mouth and will use a replaceable cartridge system that includes a filtration fabric to prevent contact spread of the virus from the saturated filter. In this design, the filters are disposable while the main component of the mask can withstand repeated sterilization, thus prolonging the life-cycle of the product and addressing shortages of N95 masks.

Read entire article HERE.

Bloomberg: Oil Engineer Helps Norway Double Respirator Capacity

An idea from a Norwegian oil engineer will help the Nordic country double the number of respirators in its hospitals to treat covid-19 patients.

The emergency respirator was developed in only three weeks and production is due to start imminently, Prime Minister Erna Solberg said at a press conference on Tuesday. Norway currently has less than 700 such machines.

Engineer and entrepreneur Eivind Gransaether came up with the idea, which was then developed by the Norwegian Defense Research Institute and private businesses Laerdal Medical AS and Servi AS. The Norwegian government has guaranteed funding for the project and ordered 1,000 respirators, some of which might ultimately be exported.

Read entire article HERE.

CNBC: WHO officials enroll first patients from Norway and Spain in ‘historic’ coronavirus drug trial

The first patients in a “historic” drug trial to test treatments for the coronavirus have been enrolled in Norway and Spain, World Health Organization officials announced Friday.

World health officials are testing four of the most promising drugs to fight COVID-19, including malaria medications chloroquine and hydroxychloroquine, an antiviral compound called Remdesivir, a combination of HIV drugs Lopinavir and Ritonavir and a combination of those drugs plus interferon-beta.

Read entire article HERE.

Hellenic Shipping: DNV GL’s remote surveys surge with 15,000 completed since launch

DNV GL introduced remote surveys in October 2018. More than 15,000 surveys have been completed remotely since then.
The impact of the global COVID-19 crisis has reinforced the value of DNV GL’s industry first remote survey services. With some 15,000 surveys and inspections undertaken since the launch in October 2018, customers have benefited from greater flexibility and efficiency through the continued digitalization and integration of DNV GL’s class services.

At DNV GL it is vital our customers continue to operate and deliver without disruptions to class services, and at the same time it is essential not to compromise the safety of crews and surveyors. While our offices, surveyors and experts remain to be in operation, remote surveys have provided the flexibility customers need, with global round the clock coverage, and improved efficiency through reduced travel times and increased availability.

Read entire article HERE.

Forbes: How Norway’s Travel Industry Is Coping Amid Coronavirus Lockdown

Tourism in Norway had been booming for a decade. Overnight stays in 2019 increased for the sixth successive year, hitting a new record of 35.2 million guest nights—a figure that excludes private rentals such as AirBnB and the ever increasing number of day visits from cruise ship passengers. Almost 170,000 people work in the tourism sector in Norway, approximately 6.7% of the country’s workforce. Everyone in the industry had expected another record-breaking year. Then came the emergency coronavirus measures implemented to try and stop the spread of COVID-19.

Since March 16, Norway’s borders have essentially been closed to all non-residents. While domestic travel remains possible, the authorities have strongly advised against all but essential travel. The recent ban on overnight stays in cabins and several municipalities introducing quarantine regulations for anyone returning home has brought the travel industry to an unprecedented halt. With the emergency measures extended until April 13, the industry—and its employees—are facing an uncertain future.

Read entire article HERE.

Press Release: Biogen Foundation Commits $10 Million to Support COVID-19 Relief Efforts in the US and Around The World

CAMBRIDGE, Mass., March 16, 2020 (GLOBE NEWSWIRE) — Biogen Inc(Nasdaq: BIIB) today announced that the Biogen Foundation has committed $10 million to support global response efforts and communities around the world impacted by the COVID-19 pandemic. The funds will be used to address immediate critical needs, with the majority of donations going to support non-profit organizations in the U.S., including Massachusetts and North Carolina, in Italy and in other impacted countries worldwide. This donation will be used to help expand testing options, ease the strain on medical systems, provide training for front line health workers and support access to necessities like food. This adds to the donation made by Biogen China to the Red Cross Society of China.

The company has also provided medical equipment and supplies to Partners HealthCare in Massachusetts, to help diagnose COVID-19 in a greater number of people. Partners HealthCare is one of the largest providers of healthcare services in the Boston area. Biogen will also be supporting Massachusetts General Hospital and Brigham and Women’s Hospital directly as they work on the front line to treat and contain the virus.

“We are deeply affected by the impact of COVID-19 globally and we understand the critical importance of access to testing and other materials to support healthcare providers,” said Michel Vounatsos, CEO at Biogen. “It is vital that we act immediately to support those who are on the front lines caring for the health and well-being in all communities affected around the world. Our hope is that this commitment will support these courageous organizations, and the vulnerable, during this unprecedented time.”

“This pandemic is precipitating a series of unprecedented challenges and it is having a critical impact in our community and on people around the world,” said Anne Klibanski, M.D., President and CEO of Partners HealthCare. “I believe it is how we rise to meet these challenges that defines us.”

About the Biogen Foundation
The Biogen Foundation supports access to science education and to essential human services for children and their families in the communities in which Biogen facilities are located. The Biogen Foundation is committed to sparking a passion for science and discovery, supporting effective science education initiatives and strengthening efforts to make science education and science careers accessible to diverse populations.

About Biogen
At Biogen, our mission is clear: we are pioneers in neuroscience. Biogen discovers, develops and delivers worldwide innovative therapies for people living with serious neurological and neurodegenerative diseases as well as related therapeutic adjacencies. One of the world’s first global biotechnology companies, Biogen was founded in 1978 by Charles Weissmann, Heinz Schaller, Kenneth Murray and Nobel Prize winners Walter Gilbert and Phillip Sharp. Today Biogen has the leading portfolio of medicines to treat multiple sclerosis, has introduced the first approved treatment for spinal muscular atrophy, commercializes biosimilars of advanced biologics and is focused on advancing research programs in multiple sclerosis and neuroimmunology, Alzheimer’s disease and dementia, neuromuscular disorders, movement disorders, ophthalmology, immunology, neurocognitive disorders, acute neurology and pain.

We routinely post information that may be important to investors on our website at www.biogen.com. Follow us on social media – TwitterLinkedInFacebookYouTube.

Read original press release HERE.

Market Watch: Ford partners with GE, 3M to build ventilators, COVID-19 protective equipment

A car maker, industrial conglomerate and Post-it Notes maker said Tuesday they are working together to help ease the COVID-19 national emergency, as they look to boost production of equipment to help prevent the spread of the novel coronavirus.

“This is such a critical time for America and the world. It is time for action and cooperation,” said Bill Ford, executive chairman at Ford Motor Co. “By coming together across multiple industries, we can make a real difference for people in need and for those on the front line of this crisis.

Read entire article HERE.

CNBC: Amazon AWS launches $20 million initiative to help fight the coronavirus

Amazon AWS announced Friday it’s setting aside an initial $20 million to help accelerate research and development of diagnostic solutions. That includes, but won’t be limited to, helping push forward a more accurate, faster coronavirus COVID-19 test. 

“One area where we have heard an urgent need is in the research and development of diagnostics, which consist of rapid, accurate detection and testing of COVID-19,” Amazon said. “Better diagnostics will help accelerate treatment and containment, and in time, shorten the course of this epidemic.

Read entire article HERE.

Press Release: Roche initiates Phase III clinical trial of Actemra/RoActemra in hospitalised patients with severe COVID-19 pneumonia

Basel, 19 March 2020- Roche (SIX: RO, ROG; OTCQX: RHHBY) today announced  we are working with the Food & Drug Administration (FDA) to initiate a randomised, double-blind, placebo-controlled Phase III clinical trial in collaboration with the Biomedical Advanced Research and Development Authority (BARDA), a part of the US Health and Human Services Office of the Assistant Secretary for Preparedness and Response (ASPR), to evaluate the safety and efficacy of Actemra®/RoActemra® (tocilizumab) plus standard of care in hospitalised adult patients with severe COVID-19 pneumonia compared to placebo plus standard of care.

This is the first global study of Actemra/RoActemra in this setting and is expected to begin enrolling as soon as possible in early April with a target of approximately 330 patients globally, including the US. The primary and secondary endpoints include clinical status, mortality, mechanical ventilation and intensive care unit (ICU) variables.

“We are initiating a clinical trial to study Actemra/RoActemra for the treatment of people hospitalised with COVID-19 pneumonia, so that we can better establish the potential role for Actemra/RoActemra in fighting this disease,” said Levi Garraway, M.D., Ph.D., Roche’s Chief Medical Officer and Head of Global Product Development. “In these unprecedented times, today’s announcement is an important example of how industry and regulators can collaborate quickly to address the COVID-19 pandemic, and we will share the results as soon as possible.”

To date, there are several independent clinical trials exploring the efficacy and safety of Actemra/RoActemra for the treatment of patients with COVID-19 pneumonia. Actemra/RoActemra has been included in the 7th updated diagnosis and treatment plan for COVID-19 issued by China’s National Health Commission (NHC) on March 3, 2020.

However, this new trial is vital because there are no well-controlled studies and limited published evidence on the safety or efficacy of Actemra/RoActemra in the treatment of patients suffering from COVID-19. In addition, Actemra/RoActemra is not currently approved for this use by any health authorities, including the US Food and Drug Administration (FDA).

In addition to initiating this trial, Roche received FDA Emergency Use Authorisation for the cobas® SARS-CoV-2 Test on March 13, 2020, to detect the novel virus that causes COVID-19 disease. Learn more here.

About the Clinical Trial
Roche is initiating a randomised, double-blind, placebo-controlled Phase III study (COVACTA) to evaluate the safety and efficacy of intravenous Actemra/RoActemra added to standard of care in adult patients hospitalised with severe COVID-19 pneumonia compared to placebo plus standard of care. The primary and secondary endpoints include clinical status, mortality, mechanical ventilation and intensive care unit (ICU) variables. Patients will be followed for 60 days post-randomisation, and an interim analysis will be conducted to look for early evidence of efficacy.

About Actemra/RoActemra
Actemra/RoActemra was the first approved anti-IL-6 receptor biologic available in both intravenous (IV) and subcutaneous (SC) formulations for the treatment of adult patients with moderate-to-severe active rheumatoid arthritis (RA). Actemra/RoActemra can be used alone or with methotrexate (MTX) in adult RA patients who are intolerant to, or have failed to respond to, other disease-modifying anti-rheumatic drugs (DMARDs). In Europe, RoActemra IV and SC are also approved for use in adult patients with severe, active and progressive RA who previously have not been treated with MTX. Actemra/RoActemra IV and SC are approved globally for polyarticular juvenile idiopathic arthritis (pJIA) and in the US and Europe for systemic juvenile idiopathic arthritis (sJIA) in children two years of age and older. Actemra/RoActemra SC injection is also the first approved therapy for the treatment of giant cell arteritis (GCA) in more than 40 countries, including the US and Europe. In the US and Europe, Actemra/RoActemra IV injection is approved for the treatment of chimeric antigen receptor (CAR) T-cell-induced severe or life-threatening cytokine release syndrome (CRS) in people two years of age and older. Actemra/RoActemra was the first approved treatment for CRS in this setting. A prefilled autoinjector ACTPen has been approved in the US and Europe. In Japan, Actemra is also approved for the treatment of Castleman’s Disease and Takayasu Arteritis. Actemra/RoActemra is part of a co-development agreement with Chugai Pharmaceutical Co., Ltd and has been approved in Japan since April 2005. Actemra/RoActemra is approved in more than 110 countries worldwide.

About Roche
Roche is a global pioneer in pharmaceuticals and diagnostics focused on advancing science to improve people’s lives. The combined strengths of pharmaceuticals and diagnostics under one roof have made Roche the leader in personalised healthcare – a strategy that aims to fit the right treatment to each patient in the best way possible.

Roche is the world’s largest biotech company, with truly differentiated medicines in oncology, immunology, infectious diseases, ophthalmology and diseases of the central nervous system. Roche is also the world leader in in vitro diagnostics and tissue-based cancer diagnostics, and a frontrunner in diabetes management.

Founded in 1896, Roche continues to search for better ways to prevent, diagnose and treat diseases and make a sustainable contribution to society. The company also aims to improve patient access to medical innovations by working with all relevant stakeholders. More than thirty medicines developed by Roche are included in the World Health Organization Model Lists of Essential Medicines, among them life-saving antibiotics, antimalarials and cancer medicines. Moreover, for the eleventh consecutive year, Roche has been recognised as one of the most sustainable companies in the Pharmaceuticals Industry by the Dow Jones Sustainability Indices (DJSI).

The Roche Group, headquartered in Basel, Switzerland, is active in over 100 countries and in 2019 employed about 98,000 people worldwide. In 2019, Roche invested CHF 11.7 billion in R&D and posted sales of CHF 61.5 billion. Genentech, in the United States, is a wholly owned member of the Roche Group. Roche is the majority shareholder in Chugai Pharmaceutical, Japan. For more information, please visit www.roche.com.

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CNBC: Thermo Fisher ships coronavirus tests, aims to produce 5 million tests a week by April

The first batch of government-authorized coronavirus tests from Thermo Fisher Scientific have shipped off and the “dramatic ramp up” in production has begun, CEO Marc Casper told CNBC Monday.

“We have already about 1.5 million tests in stock. We began shipping them yesterday and today,” Casper said in a “Mad Money” interview with Jim Cramer. “But we’re ramping up to about 2 million tests in production a week, and then over the course of April we’ll be able to get that to about 5 million tests a week in terms of production.”

Read entire article HERE.